Having been in all continents, I just find South America the most fascinating. One reason, from a media point of view, the continent gets less coverage – other than the carnivals, Colombian drugs, and Venezuelan President Victor Hugo.
If you are thinking of going to South America, consider these:
Some South American countries like Brazil require vaccination, especially yellow fever, if you are coming from certain areas of the globe – but not North America.
Some countries do not require visas from an unusual list of nationalities such as Filipinos but do require them from Americans and/or Canadians. Three countries come into mind: Suriname, Brazil and Peru.